The Global Health EDCTP3 Joint Undertaking (GH EDCTP3) builds on the first and second European and Developing Countries Clinical Trials Partnership programmes. This new joint undertaking (JU) is a partnership between the EU and the EDCTP Association, whose members are several European and African countries. The partnership will deliver new solutions for reducing the burden of infectious diseases in SSA and strengthen research capacities to prepare and respond to re-emerging infectious diseases in this region and across the world.
The European and Developing Countries Clinical Trials Partnership (EDCTP) exists to accelerate the clinical development of new or improved health technologies for the identification, treatment and prevention of poverty-related and neglected infectious diseases, including (re-)emerging diseases, particularly those affecting sub-Saharan Africa (SSA). In addition, the EDCTP funds activities for research capacity building in Africa, supporting networking and researchers’ careers and strengthening national health research systems. Furthermore, the partnership facilitates alignment of public and private funders around a common Strategic Research and Innovation Agenda.
In the context of the Commission’s priorities of contributing to the United Nations Sustainable Development Goals (SDGs), in particular Sustainable Development Goal 3, the Comprehensive Strategy with Africa, the Global Approach to Research & Innovation3 and the new EU Global Health Strategy the EU is committed to ensuring healthy lives and promoting well-being for all, to building an even stronger partnership between the two continents and to supporting the development of research and innovation capacities within Africa.
EDCTP – Europe Office
Postal and visiting address
Anna van Saksenlaan 51
2593 HW The Hague, The Netherlands
Telephone: +31 70 344 0880
EDCTP – Africa Office
P.O. Box 19070, Tygerberg 7505
Cape Town, South Africa
Francie van Zijl Drive,
Cape Town, South Africa
Telephone: +27 21 938 0690
Fax: +27 21 938 0569
Contact Form in the website
Code: 32407 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-02-01-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024
Proposals submitted to this topic should implement a master’s level training programme in a discipline relevant for the Global Health EDCTP3 JU, providing transferable R&D skills, fostering innovation and entrepreneurship, incl. commercialisation of results, Intellectual Property Rights, communication, public engagement, and citizen science. The training provided by the academic institutions is expected to be complemented by training modules provided by pharmaceutical companies. It is expected that pharmaceutical companies will join the consortium as beneficiaries and/or associated partners at a later stage. The companies are expected to bring cash or in-kind contributions to the training programme for the fellows.
The training will address the research and development value chain from pre-clinical to clinical research including pharmaceuticals and vaccines.
Code: 32393 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-06-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024
This topic focuses on innovative digital health solutions for sub-Saharan Africa. Integration of digital health innovations in national and/or regional strategies and context will be instrumental to ensure long-term impact and sustainability.
Code: 32391 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-05-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024
This topic focuses on new tools, technologies and approaches for vector control in sub-Saharan Africa.
Proposals under this topic should aim to deliver results that are directed, tailored towards, and contributing to the development and evaluation of tools, technologies and approaches for vector-borne diseases, including vector control and disease management technologies.
This topical area should be innovative interventions that target any vector-borne disease including transmission through mosquitos, ticks, flies, fleas, lice, aquatic snails, and bugs.
Code: 32389 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-04-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024
This topic focuses on Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials. Tackling AMR requires multi-modal interventions, the collaboration of many disciplines and countries. Antimicrobial stewardship (AMS) could further reduce the burden of drug-resistant infection. The WHO defines AMS as a coherent set of integrated actions which promote the responsible and appropriate use of antimicrobials to help improve patient outcomes across the continuum of care. Responsible and appropriate use of antimicrobials includes prescribing only when needed, selection of the optimal drug regime, drug dosing, route of administration and duration of treatment following proper and optimized diagnosis. These actions are complemented by the implementation of infection prevention and control (IPC), enhancing water, sanitation and hygiene (WASH), and optimizing vaccination coverage.
AMR is one of the Global Health issues which can hugely benefit from the employment of the One Health approach. AMR transmission is a critical global problem affecting humans, the environment, and animals. Hence, proposals need to have the One Health approach at their centre.
Furthermore, the availability and access to existing antibiotics is also a challenge. In particular, efforts to ensure equitable access to antibiotics in LMICs that experience the highest burden of AMR, are needed.
Code: 32387 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-03-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024
Diseases such as schistosomiasis, onchocerciasis, and other NTDs continue to affect hundreds of millions of people who are most often society’s poorest, in sub-Saharan Africa.
Many of NTDs are vector-borne diseases, have animal reservoirs and are associated with complex life cycles. The epidemiology of NTDs is complex and multifactorial, often related to environmental conditions, that makes their public-health control challenging. Pharmaceutical interventions combined with interventions such as house improvements, improved access to safe water, sanitation and hygiene (WASH) are also critical in the prevention for the majority of the NTDs, especially for Trachoma, Soil-transmitted helminthiases (STHs), Schistosomiasis and Dracunculiasis.
Therefore, accelerating development and integration of therapeutics against Neglected Tropical Diseases (NTDs) in sub-Saharan Africa.
Code: 32385 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-02-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024
This topic focuses on research on existing Malaria vaccines and development of new promising candidates. Specifically, Malaria requires a multidimensional approach, including more and better vaccine strategies. Therefore, further R&D on other promising candidates in the pipeline is required, and further research on cross-cutting issues is necessary, to ensure both pharmaceutical and non-pharmaceutical prevention strategies are part of future evidence-based malaria prevention and control measures. Synergy between researchers and other relevant stakeholders is required to develop and strengthen vaccines manufacturing capacity and to build an efficient supply chain in sub-Saharan Africa.
Code: 32383 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-01-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024
There is a strong need to achieve the 2030 UNAIDS 95-95-95 target and develop novel HIV therapeutics, novel clinical delivery modes for their administration and novel biomarkers for optimising treatment decisions in sub-Saharan Africa.
Code: 29829 | Identifier Code: HORIZON-JU-GH-EDCTP3-2023-02-02-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 27/06/2023 | End submission calls: 28/09/2023
Proposal under this topic should aim to deliver results that are directed towards, and contributing to all of the following expected outcomes:
Code: 29827 | Identifier Code: HORIZON-JU-GH-EDCTP3-2023-02-01-two-stage | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 27/06/2023 | End submission calls: 28/09/2023
Proposals submitted under this topic should aim for delivering results that are directed to all the following expected outcomes:
Code: 29129 | Identifier Code: HORIZON-JU-GH-EDCTP3-2023-01-02 | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 10/05/2023 | End submission calls: 29/06/2023
This topic focuses on the clinical trials of medical technologies that were funded by EDCTP2 and whose activities were disrupted during the COVID-19 pandemic.
Information about medical technologies can be used by health care professionals and health care systems.
Code: 29127 | Identifier Code: HORIZON-JU-GH-EDCTP3-2023-01-04 | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 10/05/2023 | End submission calls: 29/06/2023
Proposals submitted under this call topic are expected to advance knowledge on Ebola virus disease with the aim of contributing to an efficient patient management and public health response, as well as better epidemic preparedness in Africa. Special focus should be on improving our understanding of the Sudan virus disease, in view of the recent outbreak in East Africa and the lack of available interventions for this viral strain.
Code: 29125 | Identifier Code: HORIZON-JU-GH-EDCTP3-2023-01-03 | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 10/05/2023 | End submission calls: 29/06/2023
This topic is focused on the need for critical appraisal of existing health interventions, which may have been introduced and used by healthcare systems without rigorous evaluation in clinical trials. It is thus important to understand whether such interventions lead to better overall health in these populations.
Concerted efforts are needed to increase access to potentially lifesaving, cost-effective interventions to prevent and treat PRDs and other diseases such as diarrhoeal diseases, bacterial infections (especially those where antimicrobial resistance is an issue), sepsis and lower respiratory tract infections in pregnant women, newborns, and children to ensure solid evidence is produced for the recommended interventions and to enhance the use of existing interventions in these populations.
Code: 29123 | Identifier Code: HORIZON-JU-GH-EDCTP3-2023-01-05 | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 10/05/2023 | End submission calls: 29/06/2023
The aim of this call is to improve the functionality, recognition and performance of NECs and NRAs for carrying out clinical trials in SSA countries.
The projects funded under this call will support the SSA countries to establish and/or develop own robust capacities for ethics review and national medicines regulatory systems. This also includes support towards national and international collaboration in compliance with established international standards. This scheme targets proposals with active involvement of NECs and/or NRAs from SSA countries, and in particular with those countries with the highest infectious disease burden.
Code: 29120 | Identifier Code: HORIZON-JU-GH-EDCTP3-2023-01-01 | Programme name: Global Health EDCTP3 Joint Undertaking | Start submission calls: 10/05/2023 | End submission calls: 29/06/2023
The Global Health EDCTP3 Training Networks aim to train and develop skilled, innovative, and resilient African researchers, scientists, clinicians, and other public health professionals working in the area of infectious disease research. The main objective is that these professionals can face current and future clinical research challenges, efficiently carry out clinical trials, mentor young scientists, implement research results, apply knowledge into development of products and services and/or analyse data to inform policy and practice for better health for all in sub-Saharan Africa (SSA). Through the training being offered to the fellows, important research questions within the framework of the Strategic Research and Innovation Agenda of Global Health EDCTP3 will be addressed.