Programme Category
Programme Name
Programme Description
The Global Health EDCTP3 Joint Undertaking (GH EDCTP3) builds on the first and second European and Developing Countries Clinical Trials Partnership programmes. This new joint undertaking (JU) is a partnership between the EU and the EDCTP Association, whose members are several European and African countries. The partnership will deliver new solutions for reducing the burden of infectious diseases in SSA and strengthen research capacities to prepare and respond to re-emerging infectious diseases in this region and across the world.
Identifier Code
Call
Summary
Proposals submitted under this call topic are expected to advance knowledge on Ebola virus disease with the aim of contributing to an efficient patient management and public health response, as well as better epidemic preparedness in Africa. Special focus should be on improving our understanding of the Sudan virus disease, in view of the recent outbreak in East Africa and the lack of available interventions for this viral strain.
Detailed Call Description
The scope of the proposals submitted under this call topic should include one or more of the following areas:
- Clinical development of therapeutics. This can include early phase testing of candidates for safety, validation of standardised animal models that adequately recapitulate the clinical hallmarks of human infection and illness to enable acceleration of regulatory pathways for vaccines and therapeutics, or platform trial designs or networks that can be pivoted to outbreaks where they occur. Best practices for the use and deployment of intervention tools, including storage and transport should be considered.
- Clinical development of point-of-care (POC) diagnostics, ensuring rapid evaluation of POC tools based on existing technologies to allow for fast case detection and better surveillance. It should be possible that the developed diagnostic tools can easily be taken up by health care systems and health care centres, also in rural settings.
- Social sciences research to improve risk communication activities, provide responses to social dynamics of Ebola virus outbreaks and increase acceptance of the public health response and medical countermeasures.
Vulnerable populations need to be included in the clinical study population, including children, pregnant women, people with co-infections and comorbidities, older people and people living in hard-to-reach communities (unless excluded for physiologic or metabolic reasons). Collaboration and coordination with existing outbreak response initiatives and ongoing Ebola research actions are highly encouraged to facilitate knowledge exchange, collaboration, synergies, and coordination of response activities. Community engagement should be supported.
Call Total Budget
Financing percentage by EU or other bodies / Level of Subsidy or Loan
Expected EU contribution per project: €3 000 000
Thematic Categories
- Health
- Research, Technological Development and Innovation
Eligibility for Participation
- Associations
- Central Government
- International Organisations
- Local Authorities
- Other Beneficiaries
- Parliamentary Bodies
- Researchers/Research Centers/Institutions
- Semi-governmental organisations
- State-owned Enterprises
Eligibility For Participation Notes
Promotion of close communication between clinical experts, patient communities, regulators, health care workers and policy makers is expected to increase the uptake of a developed intervention and improve outbreak response.
Interaction with relevant national public health institutes and regulatory authorities, African Medicines Agency, Africa Centres for Disease Control and Prevention, World Health Organization – Regional Office for Africa and/or other regional and international relevant organisations are expected to adequately address research needs.
Call Opening Date
Call Closing Date
EU Contact Point
EDCTP – Europe Office
Postal and visiting address
Anna van Saksenlaan 51
2593 HW The Hague, The Netherlands
Telephone: +31 70 344 0880
EDCTP – Africa Office
Postal address
P.O. Box 19070, Tygerberg 7505
Cape Town, South Africa
Visiting address
Francie van Zijl Drive,
Parowvallei 7505
Cape Town, South Africa
Telephone: +27 21 938 0690
Fax: +27 21 938 0569
Contact Form in the website