Development and implementation of online monitoring and diagnostic tools for electrolysers

Closed

Code: 32452 | Identifier Code: HORIZON-JTI-CLEANH2-2024-01-04 | Programme name: 27323 | Start submission calls: 18/01/2024 | End submission calls: 17/04/2024

The scope of this topic is to further develop methods and tools for monitoring and diagnostics of electrolyser systems and demonstrate these at an industrially relevant scale (> 100 kW) on one electrolyser type. Such tools would help reduce OPEX by making dynamic operation more durable and reliable, reducing degradation on the system, and increasing the system efficiency. The commercial utilisation and exploitation should be clearly considered in the project.

Development of innovative technologies for direct seawater electrolysis

Closed

Code: 32450 | Identifier Code: HORIZON-JTI-CLEANH2-2024-01-03 | Programme name: 27323 | Start submission calls: 18/01/2024 | End submission calls: 17/04/2024

The expectations stemming from the aforementioned expected outcomes create a set of challenges to be overcome in order to produce electrolysers of various scale of power for distributed hydrogen production, performed without other than basic mechanical filtration or purification of seawater. In order to understand and tune reaction mechanisms describing the desired catalytic activities and the overall stability and selectivity, special attention needs to be paid to in-depth experimental, computational and theoretical insight into the mechanistic pathways and properties of the electrode-electrolyte interface under operating conditions. The major effort should, therefore, focus on one hand on the improvement of the hydrogen electrode to work in this harsh environment and on the other hand on the improvement of the selectivity towards the oxygen evolution at the anode electrode, as well as, to the durability issues stemming from both corrosion processes and catalyst (and membrane when applies) poisoning.

Advanced anion exchange membrane electrolysers for low-cost hydrogen production for high power range applications

Closed

Code: 32448 | Identifier Code: HORIZON-JTI-CLEANH2-2024-01-02 | Programme name: 27323 | Start submission calls: 18/01/2024 | End submission calls: 17/04/2024

The scope of this topic is to develop the next generation of anion exchange membrane electrolyser stack layout delivering hydrogen at a pressure suitable for industrial end-uses.

Guidelines for sustainable-by-design systems across the hydrogen value chain

Closed

Code: 32446 | Identifier Code: HORIZON-JTI-CLEANH2-2024-05-01 | Programme name: 27323 | Start submission calls: 18/01/2024 | End submission calls: 17/04/2024

This topic addresses the development of sustainable-by-design guidelines, including reference criteria and prioritisation of actions, for a selection of FCH systems in the joint field of safe and sustainability assessment and eco-design. These guidelines should comprehensively address both the sustainability and safety aspects of systems pertaining to the primary applications of hydrogen and fuel cell technologies.

Investigation of microbial interaction for underground hydrogen porous media storage

Closed

Code: 32444 | Identifier Code: HORIZON-JTI-CLEANH2-2024-02-01 | Programme name: 27323 | Start submission calls: 18/01/2024 | End submission calls: 17/04/2024

Different studies and projects (e.g. HYUSPRE, HYSTORIES) have assessed the feasibility of storing hydrogen in porous media geological formations. However, a comprehensive assessment of the risks (eg. production of certain corrosives compounds and other impurities) associated with the different groups of microorganisms in specific underground formations needs to be studied in detail, considering the boundary conditions specific of each site (e.g., temperature, pressure, pH, rock’s chemical composition, salinity, etc.). Related impact on rock properties (porosity, permeability, mechanical properties).
Overall this topic focuses on investigation of microbial interaction for underground hydrogen porous media storage.

Novel large-scale aboveground storage solutions for demand-optimised supply of hydrogen

Closed

Code: 32441 | Identifier Code: HORIZON-JTI-CLEANH2-2024-02-02 | Programme name: 27323 | Start submission calls: 18/01/2024 | End submission calls: 17/04/2024

Research activities under this topic should focus on novel safe, low-cost bulk storage solutions with the potential to enable demand-and application-optimised supply of H­2 on the (multi-) tons range for the various applications mentioned in the Funding&Tenders. Also, research activities should have a focus on minimising the geometrical footprint and volume of the storage system, as well as on safely preventing the accidental release of large amounts of H2 by developing inherently safe storage solutions.

Demonstration of hydrogen fuel cell-powered inland or short sea shipping

Closed

Code: 32438 | Identifier Code: HORIZON-JTI-CLEANH2-2024-03-04 | Programme name: 27323 | Start submission calls: 18/01/2024 | End submission calls: 17/04/2024

This topic aims at demonstrating, in an operational environment, fuel cell hydrogen based waterborne transport ecosystem, showing the feasibility and benefits of integrating hydrogen and hydrogen carriers into this hard to abate sector. The overarching goal is to address the ability to safely bunker hydrogen (pure or in terms of a hydrogen carrier), to store it on board and to consume it for propulsion in a waterborne environment.

Proposals should address the demonstration of fuel cell hydrogen powered inland or short sea vessels.

Innovative proton conducting ceramic electrolysis cells and stacks for intermediate temperature hydrogen production

Closed

Code: 32433 | Identifier Code: HORIZON-JTI-CLEANH2-2024-01-01 | Programme name: 27323 | Start submission calls: 18/01/2024 | End submission calls: 17/04/2024

The topic focuses on the development of new cell and stack designs aiming at improving the performance and flexibility of operation, while reducing costly ceramic-based components and critical raw materials and strategic raw materials (e.g. light and heavy rare earth materials, LREE and HREE, Ni, Co).

EU-RAIL – SNS SYNERGY: DIGITAL & AUTOMATED TESTING AND OPERATIONAL VALIDATION OF THE NEXT EU RAIL COMMUNICATION SNS

Closed

Code: 32415 | Identifier Code: HORIZON-ER-JU-2024-FA2-SNS | Programme name: 24432 | Start submission calls: 25/01/2024 | End submission calls: 07/05/2024

To successfully address the expected outcomes, the action to be funded under this topic should research, develop, and deliver all the following capabilities:

Workstream 1: Development of a future proof telecom architecture including all necessary network elements (TRL7).
Workstream 2: Testing of key functions (TRL 7).
Workstream 3: Validation and return on experience.

DIGITAL AUTOMATIC COUPLER

Closed

Code: 32413 | Identifier Code: HORIZON-ER-JU-2024-FA5 | Programme name: 24432 | Start submission calls: 25/01/2024 | End submission calls: 07/05/2024

To successfully address the expected outcomes, the Flagship Project stemming from this innovation action topic should research, develop, and deliver all the following capabilities and/or any other relevant capability within the following workstreams:

Workstream 1: DAC Interface A derailment and propelling safety tests, crash tests, climate chamber tests and initial tests to prove interchangeability of DAC coupler head/shank and draft gear across DAC solutions.
Workstream 2: Mix and match tests – initial tests to prove interchangeability of DAC interface A coupler head/shank and draft gear across DAC suppliers.
Workstream 3: Hybrid coupler for mainline and shunting locomotives, technical analysis and development of fitting solutions.
Workstream 4: Wagon Onboard Unit (WoBu).

HYPERLOOP – ROADMAP TOWARDS INDUSTRIALISATION AND HARMONIZED IMPLEMENTABLE CONCEPT

Closed

Code: 32411 | Identifier Code: HORIZON-ER-JU-2024-FA7 | Programme name: 24432 | Start submission calls: 25/01/2024 | End submission calls: 07/05/2024

To successfully address the expected outcomes, the action to be funded under this topic should research, develop, and deliver upon all following research activities:

Work-stream 1: Technical harmonisation, roadmaps on industrialisation and applicability
Work-stream 2: Design concept and validation of key sub-systems

Global Health EDCTP3 JU training fellowship with return phase

Closed

Code: 32407 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-02-01-two-stage | Programme name: 29117 | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024

Proposals submitted to this topic should implement a master’s level training programme in a discipline relevant for the Global Health EDCTP3 JU, providing transferable R&D skills, fostering innovation and entrepreneurship, incl. commercialisation of results, Intellectual Property Rights, communication, public engagement, and citizen science. The training provided by the academic institutions is expected to be complemented by training modules provided by pharmaceutical companies. It is expected that pharmaceutical companies will join the consortium as beneficiaries and/or associated partners at a later stage. The companies are expected to bring cash or in-kind contributions to the training programme for the fellows.

The training will address the research and development value chain from pre-clinical to clinical research including pharmaceuticals and vaccines.

Clinical validation of biomarkers for diagnosis, monitoring disease progression and treatment response

Closed

Code: 32404 | Identifier Code: HORIZON-JU-IHI-2024-07-03-singe-stage | Programme name: 23667 | Start submission calls: 16/01/2024 | End submission calls: 22/05/2024

Technology development or improvements to existing technologies may be required to progress these biomarkers to clinical validation. For example, there are many novel and highly innovative technologies in development (e.g. imaging, artificial intelligence (AI), omics markers, phage-based diagnostics in multiple formats among others) and their further development and validation would be a necessary element for validating their detected biomarkers in the clinic.

Furthermore, different healthcare actors (e.g. academics, clinicians, patients, health technology developers and regulators) may have different definitions and expectations on the utilities of biomarkers, and there is a need for an aligned methodological framework for scaling up the clinical validation of candidate biomarkers.

User-centric technologies and optimized hospital workflows for a sustainable healthcare workforce

Closed

Code: 32402 | Identifier Code: HORIZON-JU-IHI-2024-07-02-singe-stage | Programme name: 23667 | Start submission calls: 16/01/2024 | End submission calls: 22/05/2024

Technical and data-driven solutions have the potential to support the healthcare workforce, but their adoption has faced many challenges. While AI solutions have been proposed to support clinical decision making, operational optimization, patient empowerment, healthy lifestyle maintenance and population health management, they require further testing and validation.

Projects funded under this theme should develop or improve innovative medical technology solutions. Better integration of existing solutions and emerging technologies into (optimized) hospital workflows will improve treatment outcomes, ease workloads and maintain job satisfaction. Through collaborative design approaches that incorporate end-user feedback, solutions should aim to be ready for integration into real-world hospital environments. Overall, this theme focuses on user-centric technologies and optimized hospital workflows for a sustainable healthcare workforce.

Improving clinical management of heart disease from early detection to treatment

Closed

Code: 32399 | Identifier Code: HORIZON-JU-IHI-2024-07-01-singe-stage | Programme name: 23667 | Start submission calls: 16/01/2024 | End submission calls: 22/05/2024

This topic focuses on the improvement of clinical management of heart disease from early detection to treatment.
Heart disease includes structural heart disease (SHD), coronary artery disease (CAD), heart failure (HF) and heart arrythmias, which are common, devastating, and heterogeneous medical conditions causing a high burden in Europe and worldwide.

Development of evidence based practical guidance for sponsors on the use of real-world data / real-world evidence

Closed

Code: 32397 | Identifier Code: HORIZON-JU-IHI-2024-06-02-two-stage | Programme name: 23667 | Start submission calls: 16/01/2024 | End submission calls: 10/10/2024

This topic focuses on the development of evidence based practical guidance for sponsors on the use of real-world data / real-world evidence.

The use of real-world evidence to support decision making on the safety of medicinal products is already well established. Much knowledge exists within individual sponsors on these use-cases, but, to date, this has not been leveraged to develop practical guidance which could act as a baseline for future submissions.
To leverage the learning from individual use cases and facilitate the efficient use of RWD/RWE for regulatory, HTA, and payer submissions and to inform healthcare decision-making, structured, evidence-based, and practical guidance is needed.

Support healthcare system resilience through a focus on persistency in the treatment of chronic diseases

Closed

Code: 32395 | Identifier Code: HORIZON-JU-IHI-2024-06-01-two-stage | Programme name: 23667 | Start submission calls: 16/01/2024 | End submission calls: 10/10/2024

The scope of this topic is to improve treatment persistency among people living with chronic diseases. According to the MEDI-VOICE project funded by the European Commission, non-adherence to medication accounted for approximately 200 000 deaths annually in the European Union, and according to a World Health Organisation (WHO) report from 2003, around 50 % of people living with a chronic disease do not adhere to the prescribed medication. From a recent analysis by Kvarnström et al (2018), the major barriers for adherence to medication range from a lack of disease knowledge by the patient to logistical barriers like availability of medication and price (see list below), ultimately leading to discontinuation of medication.

Innovative digital health solutions for sub-Saharan Africa

Closed

Code: 32393 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-06-two-stage | Programme name: 29117 | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024

This topic focuses on innovative digital health solutions for sub-Saharan Africa. Integration of digital health innovations in national and/or regional strategies and context will be instrumental to ensure long-term impact and sustainability.

New tools, technologies and approaches for vector control in sub-Saharan Africa

Closed

Code: 32391 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-05-two-stage | Programme name: 29117 | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024

This topic focuses on new tools, technologies and approaches for vector control in sub-Saharan Africa.
Proposals under this topic should aim to deliver results that are directed, tailored towards, and contributing to the development and evaluation of tools, technologies and approaches for vector-borne diseases, including vector control and disease management technologies.
This topical area should be innovative interventions that target any vector-borne disease including transmission through mosquitos, ticks, flies, fleas, lice, aquatic snails, and bugs.

Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials

Closed

Code: 32389 | Identifier Code: HORIZON-JU-GH-EDCTP3-2024-01-04-two-stage | Programme name: 29117 | Start submission calls: 18/01/2024 | End submission calls: 12/09/2024

This topic focuses on Tackling Antimicrobial Resistance (AMR) through R&D in novel and existing antimicrobials. Tackling AMR requires multi-modal interventions, the collaboration of many disciplines and countries. Antimicrobial stewardship (AMS) could further reduce the burden of drug-resistant infection. The WHO defines AMS as a coherent set of integrated actions which promote the responsible and appropriate use of antimicrobials to help improve patient outcomes across the continuum of care. Responsible and appropriate use of antimicrobials includes prescribing only when needed, selection of the optimal drug regime, drug dosing, route of administration and duration of treatment following proper and optimized diagnosis. These actions are complemented by the implementation of infection prevention and control (IPC), enhancing water, sanitation and hygiene (WASH), and optimizing vaccination coverage.

AMR is one of the Global Health issues which can hugely benefit from the employment of the One Health approach. AMR transmission is a critical global problem affecting humans, the environment, and animals. Hence, proposals need to have the One Health approach at their centre.

Furthermore, the availability and access to existing antibiotics is also a challenge. In particular, efforts to ensure equitable access to antibiotics in LMICs that experience the highest burden of AMR, are needed.