Rapid reconfigurable production process chains (Made in Europe Partnership) (IA)

Closed

Code: 15972 | Identifier Code: HORIZON-CL4-2022-TWIN-TRANSITION-01-01 | Programme name: 2939 | Sub-program: Digital, Industry & Space (Cluster 4)(2021-2027) | Start submission calls: 12/10/2021 | End submission calls: 30/03/2022

In times of disrupted supply chains or rapidly changing customer demands, production lines will need to be built flexible enough to be able to handle these variations. Rapid reconfiguration technologies of more flexible systems, will enable industries with many production process steps to maintain a resilience against sudden changes in ordering and/or supplies.

Products with complex functional surfaces (Made in Europe Partnership) (RIA)

Closed

Code: 15962 | Identifier Code: HORIZON-CL4-2022-TWIN-TRANSITION-01-02 | Programme name: 2939 | Sub-program: Digital, Industry & Space (Cluster 4)(2021-2027) | Start submission calls: 12/10/2021 | End submission calls: 30/03/2022

Surface treatments are an integral part of any manufacturing process. Surface treatments include many disciplines, such as painting/coating/printing (spray, powder, dip coating, inkjet etc.), plating/implantation (electroplating, vacuum plating/coating, etc.), thermal treatments (annealing, thermo-chemical processes, etc.), laser-based treatments (annealing, texturing, etc.), additive manufacturing, micro manufacturing (micro electrical discharge machining, micro milling, etc.) chemical and electrochemical treatments (anodizing, electropolishing, chemical deposition, etc.), biochemical treatments, etching (wet etching, plasma/dry etching, also for texturing). While the integration of these treatment technologies into a manufacturing line has been well reported, the technologies as such need to be adapted for each particular profile. 

Excellence in distributed control and modular manufacturing (Made in Europe Partnership) (RIA)

Closed

Code: 15953 | Identifier Code: HORIZON-CL4-2022-TWIN-TRANSITION-01-03 | Programme name: 2939 | Sub-program: Digital, Industry & Space (Cluster 4)(2021-2027) | Start submission calls: 12/10/2021 | End submission calls: 30/03/2022

Modularity of a production system is crucial for flexibility and to allow for varying the production according to needs and circumstances by introducing, changing, and removing different process steps. While the concept of modularity is not new, there is still a vast range of production steps that cannot be considered modular, and the ones that can be considered as such are not necessarily suitable for current demands nor to be considered as a part of sustainable production regimes.

Intelligent work piece handling in a full production line (Made in Europe Partnership) (RIA)

Closed

Code: 15941 | Identifier Code: HORIZON-CL4-2022-TWIN-TRANSITION-01-04 | Programme name: 2939 | Sub-program: Digital, Industry & Space (Cluster 4)(2021-2027) | Start submission calls: 12/10/2021 | End submission calls: 30/03/2022

The global trends towards product customization have increased production complexity. It is necessary therefore, the establishement of efficient, flexible, reconfigurable and data-driven agile factories.
Products and component handling is an integral part of the manufacturing industry and its optimization increases productivity while minimizing production costs and time. There is an increasing demand for innovative smart automated handling systems.

ICT Innovation for Manufacturing Sustainability in SMEs (I4MS2) (Made in Europe Partnership) (IA)

Closed

Code: 15931 | Identifier Code: HORIZON-CL4-2022-TWIN-TRANSITION-01-06 | Programme name: 2939 | Sub-program: Digital, Industry & Space (Cluster 4)(2021-2027) | Start submission calls: 12/10/2021 | End submission calls: 30/03/2022

ICT Innovation for Manufacturing SMEs (I4MS) aims to support manufacturing SMEs and mid-caps in adopting the latest innovative digital technologies for their business operations. I4MS2 builds on I4MS and addresses more significantly a sustainable and resilient production.

Methods for assessing health-related costs of environmental stressors

Closed

Code: 15920 | Identifier Code: HORIZON-HLTH-2022-ENVHLTH-04-01 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Policy-makers face challenges when devising pollution mitigation measures and having to assess the health costs emerging from life-long exposures to environmental stressors or the benefits from clean environments. Proposed research activities should mainly aim to improve the calculation of the socio-economic costs (and/or benefits) of health impacts during the life-course associated to environmental stressors, or combinations of these, advance methodological approaches and foster their acceptance as common good practice.

New pricing and payment models for cost-effective and affordable health innovations

Closed

Code: 15918 | Identifier Code: HORIZON-HLTH-2022-IND-13-03 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Applicants for this prosposal are requested to propose new value-based pricing and reimbursement models that can help ensure equitable access to effective, efficient, affordable, and sustainable health technologies, including medicines, while supporting innovation and industrial competitiveness.
The proposals should not be limited to the study of cost-effectiveness analyses and thresholds in decision-making. They should also address long term intended and unintended consequences of pricing and reimbursement decisions.

Scaling up multi-party computation, data anonymisation techniques, and synthetic data generation

Closed

Code: 15913 | Identifier Code: HORIZON-HLTH-2022-IND-13-02 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

It is essential to speed up and facilitate innovations in the field of data-driven tools and services for wellbeing, prevention, diagnosis, treatment and follow-up of care, among others. Therefore, the proposals are expected to scale up multi-party computation, data anonymisation techniques and synthetic data generation. To ensure privacy, the data analytics should be conducted in a distributed way among processors that grant third parties access to analysis outcomes but not to the underlying data. The developers should have access to distributed testing data sources and cloud and computing resources at large scale, with a view to improving the speed and robustness of multi-party computation solutions for innovators. The aim is to allow secure GDPR-compliant data processing for research, and clinical purposes.

Enhancing cybersecurity of connected medical devices

Closed

Code: 15910 | Identifier Code: HORIZON-HLTH-2022-IND-13-01 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

The proposals are expected to help strengthening cybersecurity maintaining the performance of medical devices while preserving or enhancing safety, security and data confidentiality, integrity and availability. The applicants should tackle the cybersecurity issue of connected medical devices and in vitro diagnostic medical devices, in particular those that are connected to the internet, allow remote access to data and exchange private or proprietary data.

Pre-commercial research and innovation procurement (PCP) for building the resilience of health care systems in the context of recovery

Closed

Code: 15905 | Identifier Code: HORIZON-HLTH-2022-CARE-08-02 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

This topic prioritises areas of health care such as health promotion, preparedness, prevention, surveillance and rapid response to cross-border health threats.
Pre-commercial procurement (PCP) can boost innovation in health care systems, while building the capacity of providers and increasing resilience and preparedness in the context of cross-border public health emergencies. Through the competitive development of a range of breakthrough innovations for a concrete health care challenge, PCP can strengthen the security of the supply chain in the health care sector.

Boosting mental health in Europe in times of change

Closed

Code: 15827 | Identifier Code: HORIZON-HLTH-2022-STAYHLTH-01-01-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

Against the backdrop of a transforming Europe and in the midst of a global pandemic, the EU is committed to lead the transition to a healthier planet and a new digital world. The health and wellbeing of its citizens is a prerequisite to achieve this aspiration.

Trustworthy artificial intelligence (AI) tools to predict the risk of chronic non-communicable diseases and/or their progression

Closed

Code: 15824 | Identifier Code: HORIZON-HLTH-2022-STAYHLTH-01-04-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

This topic will support multidisciplinary research, build on broad stakeholder engagement and support proposals developing novel robust and trustworthy AI tools to enable timely personalised prevention approaches for chronic non-communicable diseases/disorders.

Prevention of obesity throughout the life course

Closed

Code: 15822 | Identifier Code: HORIZON-HLTH-2022-STAYHLTH-01-05-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

Increased efforts in research and innovation are critical for developing and testing the impact of tools, initiatives, interventions, strategies, programmes, policies and their implementation to prevent overweight/obesity. The use of best practices, harmonisation guidelines and/or standard operating procedures, developed at various levels (from local to national) in the EU and beyond, will be the foundation for new research.

Personalised blueprint of chronic inflammation in health-to-disease transition

Closed

Code: 15816 | Identifier Code: HORIZON-HLTH-2022-STAYHLTH-02-01 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Personalised approaches for disease prevention seek to determine the predisposition to disease and deliver timely and targeted prevention measures. Understanding the risk factors that trigger the health-to-disease transition is essential for delivering personalized prevention measures or reducing the burden of chronic diseases.
The later in combination with the person’s genotype, phenotype, medical history, nutritional and well-being status, life-style and/or occupational/environmental/life stressors is likely to be involved in driving the health-to-disease transition, leading to the onset of chronic diseases.

Optimising effectiveness in patients of existing prescription drugs for major diseases (except cancer) with the use of biomarkers

Closed

Code: 15814 | Identifier Code: HORIZON-HLTH-2022-TOOL-11-01 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Proposals under this topic should aim for delivering results that are directed, tailored and contributing to all of the following expected outcomes:
a) Diagnostics industries move towards market approval for companion diagnostics.
b) Regulatory authorities approve companion diagnostics and make recommendations for the prescription of existing drugs.
c) Health care providers use biomarkers with existing pharmaceuticals to treat more efficiently and cost-effectively patients, with less adverse effects.

New methods for the effective use of real-world data and/or synthetic data in regulatory decision-making and/or in health technology assessment

Closed

Code: 15812 | Identifier Code: HORIZON-HLTH-2022-TOOL-11-02 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

With the emerging use of real-world data (RWD) and synthetic data by the pharmaceutical industry and medical devices industry, regulators and HTA bodies need to perform targeted validation of claims through independent analysis. The principal aim of this topic is to address the data needs of health regulatory bodies and HTA bodies across the EU, as outlined in the recently published “HMA-EMA Joint Big Data Taskforce Phase II report: ‘Evolving Data-Driven Regulation’’ and its associated DARWIN (Data Analysis and Real World Interrogation Network) project.

Computational models for new patient stratification strategies

Closed

Code: 15808 | Identifier Code: HORIZON-HLTH-2022-TOOL-12-01-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

In the era of big and complex data, the challenge remains to make sense of the huge amount of health care research data. Computational approaches hold great potential to enable superior patient stratification strategies to the established clinical practice, which in turn are a prerequisite for the development of effective personalised medicine approaches.
The topic covers different stages in the continuum of the innovation path (i.e. translational, pre-clinical, clinical research, validation in the clinical and real-world setting, etc.), as relevant to the objectives of the proposals. The topic will support the development of the computational models driven by the end users’ needs.

Setting up a European Smart Health Innovation Hub

Closed

Code: 15803 | Identifier Code: HORIZON-HLTH-2022-IND-13-04 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Building on the recommendations from the report of the Strategic Forum for Important Projects of Common European Interest, coordination and support is needed to:
i) create a pan-European operational network as a mechanism (a European Smart Health Innovation Hub) that can assess and promote Smart Health initiatives; ii) stimulate the demand-side and the uptake of Smart Health products and services; and iii) support the development of Smart Health products and services.

Setting up a European Electronic Health Record Exchange Format (EEHRxF) Ecosystem

Closed

Code: 15800 | Identifier Code: HORIZON-HLTH-2022-IND-13-05 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Interoperability of Electronic Health Record is key for the exchange and the portability of health data in view of better health outcomes and treatments. There is a need to continue supporting the uptake of new use cases (i.e. laboratory results, medical imaging and reports, and hospital discharge reports) and take on board possible new requirements, and ultimately to bring together policy actors and stakeholders.

Pre-clinical development of the next generation of immunotherapies for diseases or disorders with unmet medical needs

Closed

Code: 15798 | Identifier Code: HORIZON-HLTH-2022-DISEASE-06-02-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

The next generation of immunotherapies are needed in order to improve and diversify the capabilities of health care for several communicable and non-communicable diseases that cannot be effectively tackled with the currently available treatments.
Proposals should build on existing knowledge in the field, when available, in order to save time and to avoid spilling resources, and could build on the knowledge of the interaction between the immune system (innate and adaptive arms) and the microbiota, or take advantage of key enabling technologies such as biotechnology and nanotechnology, advanced manufacturing, imaging, 5G, internet of things, artificial intelligence and existing databases.