Trustworthy artificial intelligence (AI) tools to predict the risk of chronic non-communicable diseases and/or their progression

Closed

Code: 15824 | Identifier Code: HORIZON-HLTH-2022-STAYHLTH-01-04-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

This topic will support multidisciplinary research, build on broad stakeholder engagement and support proposals developing novel robust and trustworthy AI tools to enable timely personalised prevention approaches for chronic non-communicable diseases/disorders.

Prevention of obesity throughout the life course

Closed

Code: 15822 | Identifier Code: HORIZON-HLTH-2022-STAYHLTH-01-05-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

Increased efforts in research and innovation are critical for developing and testing the impact of tools, initiatives, interventions, strategies, programmes, policies and their implementation to prevent overweight/obesity. The use of best practices, harmonisation guidelines and/or standard operating procedures, developed at various levels (from local to national) in the EU and beyond, will be the foundation for new research.

Personalised blueprint of chronic inflammation in health-to-disease transition

Closed

Code: 15816 | Identifier Code: HORIZON-HLTH-2022-STAYHLTH-02-01 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Personalised approaches for disease prevention seek to determine the predisposition to disease and deliver timely and targeted prevention measures. Understanding the risk factors that trigger the health-to-disease transition is essential for delivering personalized prevention measures or reducing the burden of chronic diseases.
The later in combination with the person’s genotype, phenotype, medical history, nutritional and well-being status, life-style and/or occupational/environmental/life stressors is likely to be involved in driving the health-to-disease transition, leading to the onset of chronic diseases.

Optimising effectiveness in patients of existing prescription drugs for major diseases (except cancer) with the use of biomarkers

Closed

Code: 15814 | Identifier Code: HORIZON-HLTH-2022-TOOL-11-01 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Proposals under this topic should aim for delivering results that are directed, tailored and contributing to all of the following expected outcomes:
a) Diagnostics industries move towards market approval for companion diagnostics.
b) Regulatory authorities approve companion diagnostics and make recommendations for the prescription of existing drugs.
c) Health care providers use biomarkers with existing pharmaceuticals to treat more efficiently and cost-effectively patients, with less adverse effects.

New methods for the effective use of real-world data and/or synthetic data in regulatory decision-making and/or in health technology assessment

Closed

Code: 15812 | Identifier Code: HORIZON-HLTH-2022-TOOL-11-02 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

With the emerging use of real-world data (RWD) and synthetic data by the pharmaceutical industry and medical devices industry, regulators and HTA bodies need to perform targeted validation of claims through independent analysis. The principal aim of this topic is to address the data needs of health regulatory bodies and HTA bodies across the EU, as outlined in the recently published “HMA-EMA Joint Big Data Taskforce Phase II report: ‘Evolving Data-Driven Regulation’’ and its associated DARWIN (Data Analysis and Real World Interrogation Network) project.

Computational models for new patient stratification strategies

Closed

Code: 15808 | Identifier Code: HORIZON-HLTH-2022-TOOL-12-01-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

In the era of big and complex data, the challenge remains to make sense of the huge amount of health care research data. Computational approaches hold great potential to enable superior patient stratification strategies to the established clinical practice, which in turn are a prerequisite for the development of effective personalised medicine approaches.
The topic covers different stages in the continuum of the innovation path (i.e. translational, pre-clinical, clinical research, validation in the clinical and real-world setting, etc.), as relevant to the objectives of the proposals. The topic will support the development of the computational models driven by the end users’ needs.

Setting up a European Smart Health Innovation Hub

Closed

Code: 15803 | Identifier Code: HORIZON-HLTH-2022-IND-13-04 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Building on the recommendations from the report of the Strategic Forum for Important Projects of Common European Interest, coordination and support is needed to:
i) create a pan-European operational network as a mechanism (a European Smart Health Innovation Hub) that can assess and promote Smart Health initiatives; ii) stimulate the demand-side and the uptake of Smart Health products and services; and iii) support the development of Smart Health products and services.

Setting up a European Electronic Health Record Exchange Format (EEHRxF) Ecosystem

Closed

Code: 15800 | Identifier Code: HORIZON-HLTH-2022-IND-13-05 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Interoperability of Electronic Health Record is key for the exchange and the portability of health data in view of better health outcomes and treatments. There is a need to continue supporting the uptake of new use cases (i.e. laboratory results, medical imaging and reports, and hospital discharge reports) and take on board possible new requirements, and ultimately to bring together policy actors and stakeholders.

Pre-clinical development of the next generation of immunotherapies for diseases or disorders with unmet medical needs

Closed

Code: 15798 | Identifier Code: HORIZON-HLTH-2022-DISEASE-06-02-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

The next generation of immunotherapies are needed in order to improve and diversify the capabilities of health care for several communicable and non-communicable diseases that cannot be effectively tackled with the currently available treatments.
Proposals should build on existing knowledge in the field, when available, in order to save time and to avoid spilling resources, and could build on the knowledge of the interaction between the immune system (innate and adaptive arms) and the microbiota, or take advantage of key enabling technologies such as biotechnology and nanotechnology, advanced manufacturing, imaging, 5G, internet of things, artificial intelligence and existing databases.

Vaccines 2.0 – developing the next generation of vaccines

Closed

Code: 15788 | Identifier Code: HORIZON-HLTH-2022-DISEASE-06-03-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

Proposals should aim to diversify and accelerate the global vaccine research and development pipeline, and to strengthen the current leading role of the EU in vaccine research and development. Proposals should cover those pathogens, which still lack vaccines of sufficient efficacy, but where earlier efforts have already produced promising vaccine candidates.

Development of new effective therapies for rare diseases

Closed

Code: 15786 | Identifier Code: HORIZON-HLTH-2022-DISEASE-06-04-two-stage | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 01/02/2022

Τhe number of available therapies for rare diseases remains low, as fewer than 6% of rare diseases have an approved treatment option. Τhere is an urgent unmet medical need for the development of therapies for rare diseases, where there is still no approved therapeutic option available. Therefore, proposals should aim to develop therapies for rare diseases with no approved therapeutic option.

Better financing models for health systems

Closed

Code: 15784 | Identifier Code: HORIZON-HLTH-2022-CARE-08-04 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

Proposals under this topic should aim for delivering results that are contributing to some of the following expected outcomes:

a) Decision and policymakers in the field of health care avail of new approaches to financial planning and financing mechanisms that provide flexibility to stretched health budgets.
b) Decision and policymakers in the field of health care apply cost-effective spending strategies based on the optimisation of the use of resources, while maintaining or improving health outcomes in an equitable way;
c) Decision and policymakers in the field of health care access tools that enable them to better remunerate, contract and incentivise health care professionals and providers;
d) Decision and policymakers in the field of health care take evidence-based and socially equitable health care financial decisions.

European partnership on transforming health and care systems

Closed

Code: 15781 | Identifier Code: HORIZON-HLTH-2022-CARE-10-01 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

The creation of a research and innovation (R&I) partnership with a focus on health and care systems’ transformation represents a unique strategic opportunity to bring together stakeholders, create synergies, coordinate R&I actions, facilitate the digitisation of health and care services and support the transformation of health and care systems with innovative solutions driven by knowledge and evidence.

Public procurement of innovative solutions (PPI) for building the resilience of health care systems in the context of recovery

Closed

Code: 15770 | Identifier Code: HORIZON-HLTH-2022-CARE-08-03 | Programme name: 2939 | Sub-program: Health (Cluster 1) (2021-2027) | Start submission calls: 06/10/2021 | End submission calls: 21/04/2022

This topic aims at supporting activities that are enabling or contributing to one or several expected impacts of destination 4 “Ensuring access to innovative, sustainable and high-quality health care”.
This topic prioritises areas of health care such as health promotion, preparedness, prevention, surveillance and rapid response to cross-border health threats.

Environmental observations solutions contributing to meeting “One Health” challenges

Closed

Code: 15755 | Identifier Code: HORIZON-CL6-2022-GOVERNANCE-01-09 | Programme name: 2939 | Sub-program: Food, Bioeconomy, Natural Resources, Agriculture and Environment (Cluster 6)(2021-2027) | Start submission calls: 28/10/2021 | End submission calls: 15/02/2022

The general scope of this topic is to explore areas of the One Health policy that would benefit from the use of environmental observation and how environmental observations can be used for further shaping policies in the context of e.g. human health, animal health (including zoonoses) and plant health.
A specific focus of the proposal should be on the monitoring of the evolution of ecosystem barriers in densely populated, industrialised or agricultural areas.

Assessing the nexus of extraction, production, consumption, trade and behaviour patterns and of climate change action on biodiversity in the context of transformative change

Closed

Code: 15752 | Identifier Code: HORIZON-CL6-2022-BIODIV-01-08 | Programme name: 2939 | Sub-program: Food, Bioeconomy, Natural Resources, Agriculture and Environment (Cluster 6)(2021-2027) | Start submission calls: 28/10/2021 | End submission calls: 15/02/2022

A successful proposal must develop knowledge and tools to understand the role of transformative change for biodiversity policy making, accelerate and upscale biodiversity-relevant transformative changes in our society.
With focus on assessing the nexus of extraction, production (including processing), consumption, trade and behaviour patterns, including transformative changes for climate change on biodiversity for the EU and Associated Countries, international cooperation in particular with African countries, Brazil, Latin American and Caribbean countries or the Mediterranean region is strongly encouraged.

Preparatory actions for data spaces for manufacturing

Closed

Code: 15699 | Identifier Code: DIGITAL-2021-CLOUD-AI-01-PREP-DS-MANUFACT | Programme name: 15593 | Start submission calls: 17/11/2021 | End submission calls: 22/02/2022

The preparatory action will establish a multi-stakeholder data governance, an inventory of existing data platforms for manufacturing and a blueprint for manufacturing-specific building blocks which could contribute to the long-term convergence of existing and new data-related initiatives in manufacturing by making use of the data space technical infrastructure. The preparatory actions will support the deployment of these data spaces for manufacturing, and propose sustainable business models and incentives schemes to motivate participants to share data.
The action will bring together existing national, regional and local data ecosystems, and relevant stakeholders, to join efforts and identify common principles for sharing industrial data and re-using large pools of data at the EU level.

Data Space for Mobility

Closed

Code: 15697 | Identifier Code: DIGITAL-2021-CLOUD-AI-01-PREP-DS-MOB | Programme name: 15593 | Start submission calls: 17/11/2021 | End submission calls: 22/02/2022

The objective is to contribute to the further development of the common European Mobility data space announced in the Data Strategy and in the Sustainable and Smart Mobility Strategy, built and operated in full compliance with existing EU legislation in the mobility and transport sectors. The specific aim is to support the creation of a technical infrastructure combined with governance mechanisms that will facilitate easy, cross-border access to key data resources in this area.
Data for sustainable urban mobility indicators (SUMI) and for traffic and travel information in urban and regional areas will be made available for reuse for the development of innovative services and applications, and for policymaking.

Create a European Industrial Ecosystem for Secure QCI technologies and systems

Closed

Code: 15694 | Identifier Code: DIGITAL-2021-QCI-01-INDUSTRIAL | Programme name: 15593 | Start submission calls: 17/11/2021 | End submission calls: 22/02/2022

To prepare for the industrialisation and deployment of quantum communication infrastructure (QCI) technological and operational capabilities and advanced QCI networks essential for European cybersecurity, and contribute to the development of a European industrial QCI ecosystem, including a thriving SME sector. This support is needed to contribute to European technological autonomy in the highly strategic field of quantum communication technologies.

Data Spaces Support Centre

Closed

Code: 15691 | Identifier Code: DIGITAL-2021-CLOUD-AI-01-SUPPCENTRE | Programme name: 15593 | Start submission calls: 17/11/2021 | End submission calls: 22/02/2022

The objective of this action is to set up and operate a Support Centre, which coordinates all relevant actions on sectorial data spaces and makes available (blueprint) architectures and data infrastructure requirements for the data spaces, including possible technologies, processes, standard and tools that will allow reuse of data across sectors by the public sector and European businesses, notably SMEs. It will also support the work of the envisaged Data Innovation Board in view of enhancing the interoperability of data as well as data sharing services between different sectors and domains.