Icing in the context of sustainable aviation

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Code: 38340 | Identifier Code: HORIZON-CL5-2026-01-D6-15 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

The field of aircraft icing is of particular importance because it relates to the safety of flight facing adverse weather conditions, which became increasingly extreme during the last decade.

The aviation industry is working to develop clean and sustainable aviation. There is the need to innovate while maintaining safety.

Predicting and avoiding road crashes based on Artificial Intelligence (AI) and big data

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Code: 38337 | Identifier Code: HORIZON-CL5-2026-01-D6-14 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

One of the principles of the Safe System Approach is to turn from mainly re-active to pro-active management of road safety, i.e. not to derive needs for intervention primarily from crash investigations, but to intervene before serious crashes happen.

The ubiquitous gathering of ever-growing amounts of data and their processing in the digital transport system support this idea providing valuable information on traffic situations and events. Potential data sources include amongst others: smart phones, wearables, connected vehicles, drones, road-side sensors (e.g. camera, radar), etc.

Progress in computing power, in the accuracy of location services and in video analytics are further enablers in the processing and analysis of such data in order to identify safety-critical situations or conflicts based on surrogate safety metrics.

Safety of Cyclists, Pedestrians and Users of Micromobility Devices

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Code: 38334 | Identifier Code: HORIZON-CL5-2026-01-D6-13 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

The share of trips made by active modes is increasing, which is in line with the United Nations Sustainable Development Goals.

This increase is linked to cities actively placing more focus on the mobility and safety needs of pedestrians, cyclists, e-cyclists and users of other micro-mobility device, which materialises in new regulations, and in new or improved infrastructure. However, pedestrians and cyclists remain heavily affected by crashes.

Concurrently, the use of electrically assisted devices (such as e-bikes, e-scooters, e-cargo bikes, mobility systems used by people with disabilities, etc.) – to be referred to as micromobility modes – is increasing exponentially because these modes represent an efficient means of personal mobility, as well as a new and effective mode for the last-mile delivery of goods within the city area. Micromobility modes, shared and owned, have been adopted by commuters, tourists, the elderly, food and goods delivery companies, and come in varying sizes and operating speeds.

When their use emerged, micromobility modes were associated with high hospitalisation rates, mainly for the micromobility users themselves, but also pedestrians and cyclists. While efforts have been made to regularise and standardise these vehicles, especially in the case of shared e-scooters, there is still a significant knowledge gap related to the operational safety of these vehicles in cities.

Integrating inland waterway transport in smart shipping and multimodal logistics chains

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Code: 38331 | Identifier Code: HORIZON-CL5-2026-01-D6-10 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

While the increased use of sustainable transport modes and multimodal solutions are critical levers for transport, logistics and supply chain decarbonisation, and despite obvious environmental advantages, the modal share of the EU IWT sector has remained below expectations over the last decades.

The seamless integration of inland waterway transport in multimodal supply chains requires the physical and digital connection to other land transport modes and maritime transport. Digitalisation is not a goal in itself but an important supporting development required to remain competitive and to improve the connectivity to ports, other transport modes and the clients (e.g. to keep the direct costs low and to allow synchromodal solutions).

Digital interconnectivity (with logistics systems and other digital platforms for transport) is crucial to increase the modal share of IWT in multimodal logistics chains and to be able to significantly contribute to the modal shift goals as presented in the Sustainable and Smart Mobility Strategy.

Reliable data and practices to measure and calculate transport emissions in multimodal transport chains

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Code: 38328 | Identifier Code: HORIZON-CL5-2026-01-D6-09 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

Greenhouse gas (GHG) emissions from transport represent around 25% of total man-made GHG emissions and continue to grow.

The negative impact of these is further strengthened by the existence of other external costs of transport, including air pollution, noise, congestion and accidents.

The EU, Member States and industry have made considerable efforts to reduce transport-related GHG emissions and associated external costs.

Accurate and reliable information on emissions is an important tool to increase effectiveness of specific emission reduction measures undertaken by public authorities and businesses.

Accelerating freight transport and logistics digital innovation

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Code: 38326 | Identifier Code: HORIZON-CL5-2026-01-D6-08 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

Electronic Freight Transport Information (eFTI) platforms established in line with Regulation 2020/1056 will play a central role in facilitating the implementation of business-to-authority (B2A) information exchange processes related to multimodal transport of goods.

In line with the Regulation’s requirements, common specifications for a single comprehensive data set and harmonised protocols for data sharing will ensure interoperability of the information shared electronically between actors, and the requirements for rights-based access-control system will establish safeguards for cybersecurity and trust.

The use of electronic means to exchange regulatory information is also expected to reduce administrative costs for economic operators, to enhance the efficiency of freight transport services and to facilitate green transformation of the logistics sector.

Innovative construction and maintenance, with the use of new materials and techniques, for resilient and sustainable transport infrastructure

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Code: 38323 | Identifier Code: HORIZON-CL5-2026-01-D6-07 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

The overarching policy background is the European Grean Deal, which aims to achieve climate neutrality by 2050.

In the transport area, this translates into a 90% reduction of transport-related greenhouse gas emissions by 2050.

To deliver the European Green Deal, there is a need to revise and upgrade numerous policies, including those for transport and large-scale infrastructures.

 

Federated CCAM data exchange platform (CCAM Partnership)

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Code: 38320 | Identifier Code: HORIZON-CL5-2026-01-D6-06 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

Data sharing plays a pivotal role in supporting R&I, enabling deployment, and enhancing the competitiveness of the CCAM industry.

Within the realm of data sharing, there are two distinct categories of data that are particularly pertinent:

1. mobility data, and
2. data for research and development.

The common European mobility data space aims to facilitate mobility data access and sharing, and is supported by projects, notably from the Digital Europe Programme.

Call for proposals for health data for biotech innovation leveraging the European Health Data Space

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Code: 38317 | Identifier Code: EU4H-2026-SANTE-PJ-08 | Programme name: 10993 | Start submission calls: 23/09/2025 | End submission calls: 06/01/2026

The general objective of this action is to accelerate the development and deployment of AI and digital solutions in the biotech sector driven by health data, ensuring its secure and responsible use through the EHDS and leveraging AI Factories to augment these efforts.

Approaches, verification and training for Edge-AI building blocks for CCAM Systems (CCAM Partnership)

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Code: 38315 | Identifier Code: HORIZON-CL5-2026-01-D6-05 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

CCAM-enabled vehicles are constantly sensing their surroundings on road conditions, location, nearby vehicles and infrastructure. Such data is shared in real-time, while data from other sources is received.

This needs powerful and optimised large data processing algorithms, which requires large amounts of computing power, data processing, real-time operation and high levels of security.

However, most existing AI computing tasks for automated vehicle applications are relying on general-purpose hardware, which has limitations in terms of power consumption, speed, accuracy, scalability, memory footprint, size and cost.

Hardware advancements driven by initiatives such as the Chips JU calls must be complemented by significant efforts to optimise AI algorithms for CCAM functionalities, ensuring their efficient performance on edge-specific hardware.

Call for proposals for a programme on orphan medical devices, in particular targeting paediatric patients

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Code: 38310 | Identifier Code: EU4H-2026-SANTE-PJ-07 | Programme name: 10993 | Start submission calls: 23/09/2025 | End submission calls: 06/01/2026

This action aims to support innovation in the field of medical devices by supporting non-profit organisations or consortia that provide a platform for academic bodies, scientific societies, developers of devices, in particular SMEs, and NGOs with a specific interest in innovative medical devices to help foster and guide the development of orphan devices, in particular in areas of unmet medical needs and paediatric patients.

Integration of human driving behaviour in the validation of CCAM systems (CCAM Partnership)

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Code: 38309 | Identifier Code: HORIZON-CL5-2026-01-D6-04 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

The deployment of CCAM systems in mixed traffic will mean intense interaction with all road users such as the human drivers of other vehicles as well as pedestrians and riders of two-wheelers. These interactions (including implicit and explicit communication by humans and CCAM systems) will play a crucial role in the acceptance and thereby the penetration of CCAM systems in future road transport.

CCAM systems will have to show safe and human-like driving behaviour, so that their decisions and actions can be anticipated easily by all road users, respecting the variety of typical driving behaviour across different countries as well as the need for CCAM systems to respect traffic rules and support road safety.

Call for proposals to support the development of a medicine pricing, reimbursement and access tracker through the EURIPID database

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Code: 38306 | Identifier Code: EU4H-2026-SANTE-PJ-06 | Programme name: 10993 | Start submission calls: 23/09/2025 | End submission calls: 06/01/2026

In the short term, this action will provide EURIPID members with a better overview of access, P&R measures and decisions across the Member States.

In the longer term, it is expected to support mutual learning between national authorities and help the Member States in taking better pricing and reimbursement decisions, with a view to improve access, availability, and affordability of medicines. This is in line with the recommendations in the Draghi Report on the future of European competitiveness, and with the priority to ensure supply of affordable medicines, as outlined in the mission letter from Commission President von der Leyen to the Commissioner for Health and Animal Welfare.

The proposed “pricing and reimbursement (‘P&R’) tracker” and access dashboard will allow improved monitoring of patients’ access to medicines across the Union, including for cancer treatments. Having this data available prior to the application of the proposed pharmaceutical reform, will serve to measure the baseline and subsequently the impact of the proposed measures that aim to increase access to medicines across the Union, including for cancer treatments.

Next-generation environment perception for real world CCAM operations: Error-free and secure technologies to improve energy-efficiency, cost-effectiveness, and circularity (CCAM Partnership)

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Code: 38304 | Identifier Code: HORIZON-CL5-2026-01-D6-03 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

The initial deployment of Level 4 automated vehicle services in urban and other complex settings has encountered significant challenges in environmental perception and decision-making, leading to occasional remote assistance calls, blockages and accidents that have impacted public trust.

At the same time, the increasing computing power demand is in conflict with a limited usage of energy and resources to meet sustainability requirements.

Thus, emerging large-scale demonstrations of automated vehicles should be accompanied by objective-oriented research aimed at addressing these challenges directly, while targeting improvements in performance, accuracy, reliability, and cyber-security.

Real time monitoring of regulated and non-regulated emissions from all types of vessels and other port activities in order to enforce emission limits in waterfront cities

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Code: 38301 | Identifier Code: HORIZON-CL5-2026-01-D5-17 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

There is a pressing need to measure accurately the different types of emissions in coastal and port environments located near to cities, because of their negative impact on the environment and human health.

Ports, as intricate environments showcasing a variety of vessels including novel designs, pose a challenge to the development of standardised technologies capable of collecting and assessing real-time pollutant emissions data from these ships docking at ports.

This is vital for enforcing emissions limits and validating the data for enforcement purposes.

Monitoring and Evaluation of the Societal Readiness Pilot

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Code: 38298 | Identifier Code: HORIZON-CL5-2026-01-D2-09 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

The European Commission has a strong interest in learning from the implementation of Societal Readiness actions piloted in eight topics from the Cluster 5 work programme 2025, and resulting in an estimate of eighteen projects to be implemented.

Conclusions on the pilot’s monitoring and evaluation will be the basis for the European Commission’s decision to replicate further these actions, to improve its implementation and possibly widen its use to other fields of application.

The instructions and definitions applying to pilot topics are included in the introduction of the Horizon Europe Main Work Programme 2025 for Climate, Energy and Mobility.

Call for proposals on lifelong prevention for a healthy life with focus on cardiovascular diseases

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Code: 38292 | Identifier Code: EU4H-2026-SANTE-PJ-05 | Programme name: 10993 | Start submission calls: 23/09/2025 | End submission calls: 06/01/2026

The aim of this action is to contribute to reducing the burden of non-communicable diseases, including cancer, and their risk factors across the lifespan, supporting Member States’ actions.

A European flagship initiative leveraging AI and health data for cardiovascular health and related non-communicable diseases: Advancing Risk Prediction, Prevention, Treatments, Personalised Care and Rehabilitation

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Code: 38290 | Identifier Code: EU4H-2026-SANTE-PJ-04 | Programme name: 10993 | Start submission calls: 23/09/2025 | End submission calls: 06/01/2026

Improved health outcomes: Earlier diagnosis and more targeted prevention of NCDs, leading to reduced disease progression, complications, and avoidable mortality.

Greater equity: Enhanced access to personalised diagnostics and AI-supported care pathways, especially in underserved regions or Member States with limited innovation capacity.

Efficiency and sustainability of health systems: Better use of resources through predictive and preventive approaches, reducing the burden of chronic conditions on healthcare infrastructures.

Trust in European health AI: By ensuring compliance with data protection, safety, and transparency standards, the initiative will foster trust in the responsible use of AI for health in line with the AI Act and EHDS Regulation. It will also support the uptake — and where relevant, the development — of specifications and standards foreseen under both frameworks, notably for interoperability, risk management and data governance

Accelerated multi-physical and virtual testing for battery aging, reliability, and safety evaluation (Batt4EU Partnership)

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Code: 38283 | Identifier Code: HORIZON-CL5-2026-01-D2-05 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

This topic aims to reduce development costs and time to market of new battery systems by accelerated multi-physical and virtual testing. Current test strategies are still very time consuming and costly due to the need to understand the impact of multi-physical operational loads (electric, thermal, mechanical, etc.), potential failure modes, ageing and misuse on the safety and reliability of battery cells and modules.

To overcome these barriers, new multi-physical test strategies supplemented by virtual testing are required taking into account the most impactful parameters on ageing, reliability and safety and their dependencies.

Integrating advanced materials, cell design and manufacturing development for high-performance batteries aimed at mobility (Batt4EU Partnership)

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Code: 38280 | Identifier Code: HORIZON-CL5-2026-01-D2-04 | Programme name: 2939 | Sub-program: Climate, Energy and Mobility (Cluster 5)(2021-2027) | Start submission calls: 25/09/2025 | End submission calls: 20/01/2026

The scope covers quasi-solid and all-solid-state lithium-ion battery technologies (up to 5% liquid electrolyte weight percentage) which encompasses Si-C composite anodes or lithium metal anodes.