Tackling high-burden for patients, under-researched medical conditions

Closed

Programme Category

EU Competitive Programmes

Programme Name

Horizon Europe (2021-2027)

Programme Description

Horizon Europe is the European Union (EU) funding programme for the period 2021 – 2027, which targets the sectors of research and innovation. The programme’s budget is around € 95.5 billion, of which € 5.4 billion is from NextGenerationEU to stimulate recovery and strengthen the EU’s resilience in the future, and € 4.5 billion is additional aid.

Programme Details

Identifier Code

HORIZON-HLTH-2024-DISEASE-03-14-two-stage

Call

Tackling high-burden for patients, under-researched medical conditions

Summary

A number of medical conditions fail to be recognized and/or correctly diagnosed in a significant proportion of patients. Consequently, they are undertreated and can often become a chronic burden to the patient. These medical conditions may be under-researched despite their high prevalence. This topic excludes rare diseases.

Detailed Call Description

Proposals should address all of the following aspects:

  • Proposals should address the gaps in robust, scientific evidence for improved policies and practices to tackle such medical condition(s), and aim at identifying the pathophysiological mechanism(s) (e.g. genetic, cellular and molecular) and potential risk factors (e.g. psychological and environmental) of the medical condition(s) through basic, pre-clinical and/or clinical research. These efforts should underpin the development of diagnostics, therapeutics, and/or preventive strategies for the condition.
  • Proposals should demonstrate that the medical condition(s) under study is/are insufficiently understood, inaccurately diagnosed or inadequately treated in a significant proportion of patients, and as such represent a high burden for patients and society. This could be through referencing key literature.
  • Sex and gender aspects, age, ethnicity, socio-economic, lifestyle and behavioural factors should be taken into consideration. In addition, the emotional and societal long-term effects of these chronic disorders for the affected individuals should be addressed.
  • Where applicable, the development of biomarkers and other technologies for diagnosis, monitoring in patients, and stratification of patient groups should be considered.
  • Where applicable, the development of clinically relevant, (non-)human model systems that can complement clinical investigations should be considered.
  • Exploitation of existing data, biobanks, registries and cohorts is expected, together with the generation of new (e.g. genomics, epigenomics, transcriptomics, proteomics) data.
  • To enable sharing of samples, quality data and advanced analytical tools, it is encouraged to make use of existing infrastructures developed at the European or national level.
  • Inclusion of patients or patient organisations in the research is strongly encouraged, to ensure that their views are considered.

Call Total Budget

€25.00 million

Financing percentage by EU or other bodies / Level of Subsidy or Loan

100%

EU contribution per project: €6.00 and €7.00 million

Thematic Categories

  • Health
  • Research, Technological Development and Innovation

Eligibility for Participation

  • Associations
  • Central Government
  • Large Enterprises
  • Legal Entities
  • Private Bodies
  • Researchers/Research Centers/Institutions
  • Semi-governmental organisations
  • Small and Medium Enterprises (SMEs)
  • State-owned Enterprises

Eligibility For Participation Notes

SME participation is strongly encouraged.

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

Call Opening Date

26/04/2023

Call Closing Date

19/09/2023

National Contact Point(s)

Research and Innovation Foundation
29a Andrea Michalakopoulou, 1075 Nicosia,
P.B. 23422, 1683 Nicosia
Telephone: +357 22205000
Fax: +357 22205001
Email: support@research.org.cy
Websitehttps://www.research.org.cy/en/

Contact Persons:
George Christou
Scientific Officer
Email: gchristou@research.org.cy

Ioannis Theodorou
Scientific Officer
Telephone: +357 22 205 038
Email: itheodorou@research.org.cy

(Publish Date: 07/04/2023-for internal use only)

EU Contact Point

European Commission, Directorate-General for Research and Innovation

https://ec.europa.eu/info/departments/research-and-innovation_en#contact