Prevention and mitigation of misuse of synthetic biology for bioterrorism purposes

Opened

Programme Category

EU Competitive Programmes

Programme Name

Horizon Europe (2021-2027)

Programme Description

Horizon Europe is the European Union (EU) funding programme for the period 2021 – 2027, which targets the sectors of research and innovation. The programme’s budget is around € 95.5 billion, of which € 5.4 billion is from NextGenerationEU to stimulate recovery and strengthen the EU’s resilience in the future, and € 4.5 billion is additional aid.

Programme Details

Identifier Code

HORIZON-CL3-2026-01-FCT-06

Call

Prevention and mitigation of misuse of synthetic biology for bioterrorism purposes

Summary

The rising threat of bioterrorism is driven by recent scientific advancements, notably by growing accessibility of synthetic biology, genetic engineering, related commercial services and public databases, which in turn enhance their obtainability to non-state actors and individuals with malicious intentions.

The proliferation of do-it-yourself biohacking and community laboratories, including gene editing and sequencing technology, dropping costs of equipment and increased simplicity of use may inadvertently facilitate knowledge and skills dissemination about biological threats and open new pathways for bioterrorism.

Challenges in detection, particularly the lengthy incubation periods of biological agents, underscore the urgent need for improved identification technologies to allow for timely intervention and reduce potential mass casualties, considering both characterization through advanced tools by expert labs and simple deployable methods. Given that properly weaponized biological agents can be more lethal than nuclear weapons, their cross-border implications warrant focused attention. Recent incidents involving biotoxins across various European countries illustrate the feasibility of biological attacks.

The increasing weaponisation of drones highlights an alarming trend that could extend to biological agents, further complicating threat landscapes. The potential economic and social consequences of biological attacks necessitate robust prevention and preparedness measures to mitigate overwhelming impacts on healthcare systems and society at large.

Detailed Call Description

Proposals are expected to address, in a lawful manner, the emerging threats of bioterrorism in Europe, particularly in the context of synthetic biology. Recognising bioterrorism as a low-probability but high-impact event, consortia should review current and future risks, flag areas requiring reinforced monitoring, as well as identify missing regulatory frameworks necessary for ensuring public security and safety. Furthermore, proposals should bring together diverse consortia to enhance our understanding, prevention, preparedness, and response to bioterrorism and create a comprehensive approach to this pressing issue.

Coordination among the successful proposals from this topic should be envisaged to avoid duplication and to exploit complementarities as well as opportunities for increased impact. In this topic the integration of the gender dimension (sex and gender analysis) in research and innovation content should be addressed only if relevant in relation to the objectives of the research effort.

Proposals funded under this topic are expected to provide ideas on how they would engage with the Europol Innovation Lab during the lifetime of the project. Similarly, if the proposals concern drug-related issues, they are expected to engage with the EU Drugs Agency during the lifetime of the project, including validating the outcomes.

Finally, proposals are expected to address all applicable considerations expressed in the Introduction of the Fighting Crime and Terrorism Destination.

Technology Readiness Level – Technology readiness level expected from completed projects

Call Total Budget

€3.000.000

Financing percentage by EU or other bodies / Level of Subsidy or Loan

100%

Expected EU contribution per project: €3.00 million

Thematic Categories

  • Health
  • Information and Communication Technologies
  • Information Technology
  • Justice - Security
  • Public Administration
  • Research, Technological Development and Innovation
  • Social Affairs & Human Rights

Eligibility for Participation

  • Central Government
  • Educational Institutions
  • Legal Entities
  • NGOs
  • Non Profit Organisations
  • Other Beneficiaries
  • Researchers/Research Centers/Institutions
  • Services Providers
  • Small and Medium Enterprises (SMEs)
  • State-owned Enterprises

Eligibility For Participation Notes

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects.

Call Opening Date

06/05/2026

Call Closing Date

05/11/2026

National Contact Point(s)

Research and Innovation Foundation

29a Andrea Michalakopoulou, 1075 Nicosia,
P.B. 23422, 1683 Nicosia
Telephone: +357 22205000
Fax: +357 22205001
Email: support@research.org.cy
Websitehttps://www.research.org.cy/en/

Contact Person:

Christakis Theocharous
Scientific Officer A’
Telephone: +357 22 20 50 29
Email: ctheocharous@research.org.cy