Better understanding of the impact of risk factors and health determinants on the development and progression of cancer

Closed

Programme Category

EU Competitive Programmes

Programme Name

Horizon Europe (2021-2027)

Programme Description

Horizon Europe is the European Union (EU) funding programme for the period 2021 – 2027, which targets the sectors of research and innovation. The programme’s budget is around € 95.5 billion, of which € 5.4 billion is from NextGenerationEU to stimulate recovery and strengthen the EU’s resilience in the future, and € 4.5 billion is additional aid.

Programme Details

Identifier Code

HORIZON-MISS-2021-CANCER-02-03

Call

Better understanding of the impact of risk factors and health determinants on the development and progression of cancer

Summary

This topic will contribute to the achievement of the mission’s goal through a better understanding of the impact of risk factors and health determinants on the development and progression of cancer (including metastasis). The focus should be on poorly understood cancers and cancer subtypes, including in children and adolescents.

Detailed Call Description

There is a need to better understand which risk factors and determinants affect the development and progression of cancer and how.

Proposals should address all of the following:

  • Develop a systematic understanding of cellular processes with a focus on the transition from a healthy state to cancer initiation and progression, at the individual or population level.
  • Demonstrate access to and use of multiple comprehensive databases in and well beyond health research and health domains, such as lifestyle, omics, clinical, indoor and outdoor exposure, environmental, urban areas and sprawl, climate, agricultural crop and land use, geo-positioning, and remote sensing. Proposals should build on longitudinal cohorts, case-control studies, biobanks, registries and many other initiatives, and use state-of-the art digital tools for data analyses and modelling, wherever possible.
  • Analyse and integrate existing knowledge and high-quality data from biomedical and clinical studies, using advanced technologies such as computer modelling, AI and machine learning with the objective to identify factors and determinants triggering the transition from the healthy state to the initiation and progression of poorly understood cancers and cancer subtypes, including in children and adolescents.
  • The influence of age, including in utero and early-life factors and determinants; environmental factors; genetic and epigenetic risk; socio-economic status; behavioural, including lifestyle risk factors; as well as social, cultural, sex and gender aspects including inequalities, should be taken into account across all aspects mentioned above.

Call Total Budget

€54,65 million

Financing percentage by EU or other bodies / Level of Subsidy or Loan

100%

EU Contribution per project: between €4,00 and €15,00 million

Thematic Categories

  • Health
  • Research, Technological Development and Innovation

Eligibility for Participation

  • Central Government
  • Researchers/Research Centers/Institutions
  • State-owned Enterprises

Call Opening Date

22/12/2021

Call Closing Date

26/04/2022

National Contact Point(s)

Research and Innovation Foundation
29a Andrea Michalakopoulou, 1075 Nicosia
P.O.Box 23422, 1683 Nicosia
Telephone: +357 22205000
Email Address: support@research.org.cy
Website: https://www.research.org.cy/en/

Mr Marinos Fotiadis
Contact Phone: 22 205 048
E-mail: mphotiades@research.org.cy
Website: https://www.research.org.cy/

Dr Ioannis Theodorou
Contact Phone: 22 205 038
E-mail: itheodorou@research.org.cy
Website: https://www.research.org.cy/

(Publish Date: 05/01/2022-for internal use only)

EU Contact Point

European Commission, Directorate-General for Research and Innovation

https://ec.europa.eu/info/departments/research-and-innovation_en#contact