For their proposed activities applicants should clearly identify a disease area of high unmet public health need1 taking into account comorbidities and/or functional status, and explain their choice with empirical evidence where possible.

Applicants should also aim to deliver the following:

• Public release of a set of minimum technical requirements for the developed platform/tools that includes interoperability, connectivity, data protection, cybersecurity and authentication/identification requirements that need to be met to allow the efficient integration of additional data from new devices/sensors/sources into the decision-support system after the project ends.
• Sustainable, ideally open-source tools that help ensure the quality and FAIRness of data at source (e.g., automated tools to help data entry, semantic coding, and data management in particular in registries and databases maintained by healthcare professionals/providers and research institutions) as well as methodologies, quality standards and metrics to assess data quality.
• Sustainable tools to increase cross-border and cross-sector interoperability of health data from the diverse sources mentioned above. Ideally, these tools use open exchange formats and take into account relevant EU initiatives including the eHealth Digital Services Infrastructure (eHDSI)2 and the European Electronic Health Record Exchange Format (EEHRxF)
• Sustainability plan/business model to ensure the long-term impact of the project results.