A European flagship initiative leveraging AI and health data for cardiovascular health and related non-communicable diseases: Advancing Risk Prediction, Prevention, Treatments, Personalised Care and Rehabilitation

Opened

Programme Category

EU Competitive Programmes

Programme Name

EU4Health Programme 2021-2027

Programme Description

The Programme aims to improve and promote health in the Union to reduce the burden of communicable and non-communicable diseases by:

  • protecting people from serious cross-border health threats
  • improving the availability, accessibility and affordability of medicines, medical devices and other crisis-related products in the EU
  • strengthening national health systems
Programme Details

Identifier Code

EU4H-2026-SANTE-PJ-04

Call

A European flagship initiative leveraging AI and health data for cardiovascular health and related non-communicable diseases: Advancing Risk Prediction, Prevention, Treatments, Personalised Care and Rehabilitation

Summary

Improved health outcomes: Earlier diagnosis and more targeted prevention of NCDs, leading to reduced disease progression, complications, and avoidable mortality.

Greater equity: Enhanced access to personalised diagnostics and AI-supported care pathways, especially in underserved regions or Member States with limited innovation capacity.

Efficiency and sustainability of health systems: Better use of resources through predictive and preventive approaches, reducing the burden of chronic conditions on healthcare infrastructures.

Trust in European health AI: By ensuring compliance with data protection, safety, and transparency standards, the initiative will foster trust in the responsible use of AI for health in line with the AI Act and EHDS Regulation. It will also support the uptake — and where relevant, the development — of specifications and standards foreseen under both frameworks, notably for interoperability, risk management and data governance

Detailed Call Description

The initiative is structured around two complementary and mutually reinforcing objectives. Together, they aim to lay the foundations for a European model of AI-enabled cardiovascular and comorbid chronic disease care, grounded in high-quality health data and real-world validated solutions.

Objective 1 — Leveraging Health Data for AI Applications in Cardiovascular and Related Chronic Diseases The first objective is to structure, federate, and enable access to high-quality health data across the Union to support the development, training, validation, and deployment of AI tools focused on cardiovascular diseases and related non-communicable diseases (such as diabetes and obesity). This will align with and prepare for the future application the EHDS, which provides the regulatory and technical framework to enable the secure, privacy preserving, and interoperable secondary use of health data across Member States.

Objective 2 — Deploying AI Solutions for Risk Prediction, Prevention, Treatments, and Personalised Care The second objective is to identify, validate, and scale up mature AI applications capable of improving the risk prediction, early detection, personalised prevention, treatment, and rehabilitation of cardiovascular and related chronic diseases.

This initiative aims to leverage AI and health data to accelerate the early detection, prediction, personalised prevention, integrated management and rehabilitation of CVDs and related NCDs, including rare and complex forms.

Call Total Budget

€20.000.000

Financing percentage by EU or other bodies / Level of Subsidy or Loan

Indicative project budget: €20.000.000

The costs will be reimbursed at the funding rate fixed in the Grant Agreement (60%).
You can apply for a higher project funding rate (80%) if your project is of ‘exceptional utility’, i.e. concerns:

  • actions where at least 30 % of the budget is allocated to Member States (or EU4H associated countries) whose GNI per inhabitant is less than 90% of the EU average or
  • actions with bodies from at least 14 Member States (or EU4H associated countries) and where at least four are from Member States (or EU4H associated countries) whose GNI per inhabitant is less than 90% of the EU average.

Grants may NOT produce a profit (i.e. surplus of revenues + EU grant over costs).
For-profit organisations must declare their revenues and, if there is a profit, we will deduct it from the final grant amount.

Thematic Categories

  • Health
  • Information Technology
  • Research, Technological Development and Innovation

Eligibility for Participation

  • Associations
  • Businesses
  • Central Government
  • Educational Institutions
  • International Organisations
  • Large Enterprises
  • Legal Entities
  • NGOs
  • Non Profit Organisations
  • Other Beneficiaries
  • Private Bodies
  • Researchers/Research Centers/Institutions
  • Semi-governmental organisations
  • Services Providers
  • Small and Medium Enterprises (SMEs)
  • State-owned Enterprises
  • Training Centres

Eligibility For Participation Notes

In order to be eligible, the applicants (beneficiaries and affiliated entities) must be legal entities (public or private bodies) established in EU Member States (including overseas countries and territories (OCTs)) or EEA countries and countries associated to the EU4Health Programme (list of participating countries).

For topic EU4H-2026-SANTE-PJ-04: Proposals must be submitted by a consortium of at least 5 beneficiaries from 5 different eligible countries.

Type of applicants targeted: Networks of experts such as European Reference Networks (ERNs), European societies or other recognised EU-level collaborations in cardiology and public health; Civil Society Organisations: Associations, Foundations and NGOs; Enterprises (incl. social enterprises and not for profit) in the field of public health; Private entities (for profit/not for profit); Public authorities, such as ministries of health, regional health agencies, or health insurance bodies actively engaged in public health initiatives.); Established networks in the field of public health, such as European or transnational organisations recognised under Union law.

Call Opening Date

23/09/2025

Call Closing Date

06/01/2026

National Contact Point(s)

Ministry of Health, Department of European Affairs

Telephone: 22605300/301, 22605617, 22605718

Address: Corner of Prodromou 1 & Chilonos 17 1448 Nicosia, Cyprus

Ms MAKRIGIORGI Elena
Email: emakrigiorgi@moh.gov.cy

EU Contact Point

For help related to this call, please contact: HADEA-HP-CALLS@ec.europa.eu