Understanding the effects of environmental exposure on the risk of paediatric, adolescent and young adult cancers
Programme Category
Programme Name
Programme Description
Horizon Europe is the European Union (EU) funding programme for the period 2021 – 2027, which targets the sectors of research and innovation. The programme’s budget is around € 95.5 billion, of which € 5.4 billion is from NextGenerationEU to stimulate recovery and strengthen the EU’s resilience in the future, and € 4.5 billion is additional aid.
Identifier Code
Call
Summary
This topic contributes to the Cancer Mission objectives by improving the understanding of the impact of environmental exposures including, their interaction with other relevant factors on cancer onset and progression and/or other relevant health outcomes along the cancer patient journey.
The age group of interest for this topic includes children, adolescents and young adults (less than 40 years of age at first cancer diagnosis).
Detailed Call Description
Applicants should take advantage of technological advances which have opened up new opportunities to collect, combine and analyse large datasets of diverse types, offering new possibilities to design epidemiological studies to understand the mechanistic contribution of environmental factors, in combination with other individual and contextual factors as appropriate. Innovative and data intensive approaches are expected for the identification of time windows of susceptibility and of robust biomarkers of cumulative environmental exposure.
The applicants should address several of the following activities:
- Identify, validate and document different types (and/or combinations) of biomarkers for the development of robust quantitative measures of the effects of cumulative environmental exposures associated with cancer onset;
- Elaborate and test cost effective approaches for measuring biomarkers of cumulative environmental exposure in large paediatric, adolescent and young adult populations, also by applying new analytical tools and novel methods of analysis;
- Identify individual signatures (e.g. based on genetic, epigenetic, multi-omic characteristics), and time windows conferring susceptibility to environmental hazards associated with cancer onset and progression in children, adolescent and young adults at different stages of the life course;
- Identify clinical states, lifestyle and socio-economic factors and circumstances that increase the risk of adverse health outcomes associated with exposure to environmental hazards in different time windows in young cancer patients;
- Develop new tools and methods to combine and analyse multimodal data, including the application of novel data-intensive methods of analysis, while ensuring interoperability with the future UNCAN.eu research platform and taking advantage of current European research infrastructures.
Call Total Budget
Financing percentage by EU or other bodies / Level of Subsidy or Loan
100%
Expected EU contribution per project: between €6.00 and €7.00 million.
Thematic Categories
- Environment and Climate Change
- Health
- Other Services
- Research, Technological Development and Innovation
Eligibility for Participation
- Educational Institutions
- Legal Entities
- Natual person / Citizen / Individual
- Non Profit Organisations
- Other Beneficiaries
- Private Bodies
- Researchers/Research Centers/Institutions
- Services Providers
- Small and Medium Enterprises (SMEs)
Eligibility For Participation Notes
The Joint Research Centre (JRC) may participate as member of the consortium selected for funding.
The following exceptions apply: subject to restrictions for the protection of European communication networks.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects.
Call Opening Date
Call Closing Date
National Contact Point(s)
Research and Innovation Foundation
Address: 29a Andrea Michalakopoulou, 1075 Nicosia, P.B. 23422, 1683 Nicosia
Telephone: +357 22205000
Fax: +357 22205001
Email: support@research.org.cy
Website: https://www.research.org.cy/en/
Contact Person:
Mr. George Christou
Scientific Officer
Email: gchristou@research.org.cy