Pandemic preparedness and response: Immunogenicity of viral proteins of viruses with epidemic and pandemic potential

Closed

Programme Category

EU Competitive Programmes

Programme Name

Horizon Europe (2021-2027)

Programme Description

Horizon Europe is the European Union (EU) funding programme for the period 2021 – 2027, which targets the sectors of research and innovation. The programme’s budget is around € 95.5 billion, of which € 5.4 billion is from NextGenerationEU to stimulate recovery and strengthen the EU’s resilience in the future, and € 4.5 billion is additional aid.

Programme Details

Identifier Code

HORIZON-HLTH-2023-DISEASE-03-18

Call

Pandemic preparedness and response: Immunogenicity of viral proteins of viruses with epidemic and pandemic potential

Summary

Proposals under this topic should identify targets for optimal vaccine design for those pathogens where information on host-pathogen interaction and viral surface structures is already available. It is necessary to determine the extent of genetic variation with a view to develop vaccines with variant efficacy. In addition, it is necessary to develop animal and alternative models for the testing of vaccine candidates and for the kinetics, strength, breadth and persistence of the immune response. Proposals should focus on the following viruses: Hendra and Nipah Virus, Lassa virus, Crimean Congo haemorrhagic fever virus, Rift Valley fever virus, Ebola and Marburg virus, Dengue virus, Yellow Fever virus, Zika virus, West Nile fever virus and Chikungunya virus.

Detailed Call Description

Proposals should provide innovative approaches with the aim to diversify and accelerate the global pandemic preparedness research and development pipeline for emerging and re-emerging viral infections, and to strengthen the role of the EU in therapeutic research and development, and therefore contributing to the work of the European Health Emergency Preparedness and Response Authority (HERA).

Proposals should address several of the following areas:

  • Identification of key antigenic targets for the priority pathogens as mentioned above.
  • Improvement or, if necessary, establishment of animal models for the testing of vaccine candidates where alternative models are not available.
  • Characterisation of the immunogenicity of antigenic targets in appropriate animal or alternative models and in pre-clinical tests.
  • Inclusion, if possible, of proof-of-concept studies in humans of the vaccine candidate.

Applicants envisaging to include clinical studies should provide details of their clinical studies in the dedicated annex using the template provided in the submission system.

Call Total Budget

€ 50,00 million

Financing percentage by EU or other bodies / Level of Subsidy or Loan

100%

Contribution per project: between €7,00 and €8,00 million

Thematic Categories

  • Health
  • Research, Technological Development and Innovation

Eligibility for Participation

  • Associations
  • Other Beneficiaries
  • Private Bodies
  • Researchers/Research Centers/Institutions
  • State-owned Enterprises
  • Training Centres

Eligibility For Participation Notes

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding.

Call Opening Date

12/01/2023

Call Closing Date

13/04/2023

National Contact Point(s)

Research and Innovation Foundation
29a Andrea Michalakopoulou, 1075 Nicosia
P.O.Box 23422, 1683 Nicosia

Telephone: +357 22205000
Email Address: support@research.org.cy
Website: https://www.research.org.cy/en/

Contact Persons:
George Christou

Scientific Officer
Email: gchristou@research.org.cy

Ioannis Theodorou
Scientific Officer
Telephone: +357 22 205 038
Contact Email: itheodorou@research.org.cy

(Publish Date: 08/02/2023-for internal use only)

EU Contact Point

European Commission, Directorate-General for Research and Innovation

https://ec.europa.eu/info/departments/research-and-innovation_en#contact