Global coordination of exposome research

Closed

Programme Category

EU Competitive Programmes

Programme Name

Horizon Europe (2021-2027)

Programme Description

Horizon Europe is the European Union (EU) funding programme for the period 2021 – 2027, which targets the sectors of research and innovation. The programme’s budget is around € 95.5 billion, of which € 5.4 billion is from NextGenerationEU to stimulate recovery and strengthen the EU’s resilience in the future, and € 4.5 billion is additional aid.

Programme Details

Identifier Code

HORIZON-HLTH-2023-ENVHLTH-02-04

Call

Global coordination of exposome research

Summary

The concept of the exposome refers to the totality of environmental exposures from conception onwards, including its external (e.g. diet, lifestyle, occupational and environmental factors) and internal components (e.g. epigenomics, metabolomics).Developing a comprehensive Human Exposome Project would present a fundamental shift in looking at health, by moving research away from ‘one exposure, one disease’ understanding to a more complex picture upon which to build solid, cost-effective preventive actions and policies.
The network of projects aims to study the combination of exposures to pollutants and other stressors, across different life stages and socio-economic conditions, via a number of exposure vehicles such as consumption patterns, lifestyle and working and living environment, and their collective effect on human health.

Detailed Call Description

At the international level, some related activities are ongoing in, e.g., the US (National Institute for Environmental Health Sciences) and Japan. Currently, there is only sporadic cooperation initiatives between the ongoing research at the EU level and important research groups outside Europe. However, in order to fulfil the promise of deciphering the human exposome, a large-scale effort similar to the Human Genome Project could be envisaged, for which a preparatory coordination and support action would be highly useful to identify and discuss the research needs and specific areas of potential cooperation at the global level. Additionally, both at the European and global level better coordination is essential to foster new opportunities to collect, harmonise, combine and analyse large data sets emanating from new and evolving technologies. This offers also new possibilities to understand the pathways leading from a multitude of environmental exposures to the global health burden of common chronic diseases. Standardisation and interoperability of data is also needed to assure access to quality data sources at the European and global level.

Proposals should cover, among others, most of the following activities:

  • Proposal for a common agreed conceptual framework for the exposome;
  • Proposal for options for a global governance structure for a Global Human Exposome Network taking advantage of and connecting to the existing research infrastructures and services in the area of the Exposome at the European level;
  • Agreed technologies needed to decipher the external and internal exposome, support longitudinal studies and potential for international cooperation;
  • Proposal for data mining, analysis, opportunities for harmonisation, interoperability, and standardisation in data collection, knowledge storage and transfer, and bioinformatics needs at the European and global level;
  • Cooperation between population and patient cohorts, integrating a large number of variables and comprehensive environmental datasets, and biobanks, also covering the perinatal period;
  • Facilitation of the regulatory uses of results including for regulatory science and risk assessment.

Call Total Budget

€3,00 million

Financing percentage by EU or other bodies / Level of Subsidy or Loan

100%

Contribution per project: €3,00 million

Thematic Categories

  • Environment and Climate Change
  • Health
  • Research, Technological Development and Innovation

Eligibility for Participation

  • Other Beneficiaries
  • Researchers/Research Centers/Institutions

Eligibility For Participation Notes

In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, legal entities established in the United States of America may exceptionally participate as a beneficiary or affiliated entity, and are eligible to receive Union funding.

Coordinators of projects must be legal entities established in an EU Member State or Associated Country.

The following additional eligibility criteria apply:
In order to achieve the expected objectives, namely the establishment of a forward-looking cooperation framework in the area of the exposome, the consortium must include at least one legal entity established in a country other than a Member State or an Associated Country.

If projects use satellite-based earth observation, positioning, navigation and/or related timing data and services, beneficiaries must make use of Copernicus and/or Galileo/EGNOS (other data and services may additionally be used).

Call Opening Date

12/01/2023

Call Closing Date

13/04/2023

National Contact Point(s)

Research and Innovation Foundation
29a Andrea Michalakopoulou, 1075 Nicosia
P.O.Box 23422, 1683 Nicosia

Telephone: +357 22205000
Email Address: support@research.org.cy
Website: https://www.research.org.cy/en/

Contact Persons:
George Christou

Scientific Officer
Email: gchristou@research.org.cy

Ioannis Theodorou
Scientific Officer
Telephone: +357 22 205 038
Contact Email: itheodorou@research.org.cy

(Publish Date: 07/02/2023-for internal use only)

EU Contact Point

European Commission, Directorate-General for Research and Innovation

https://ec.europa.eu/info/departments/research-and-innovation_en#contact