Horizon Europe is the European Union (EU) funding programme for the period 2021 – 2027, which targets the sectors of research and innovation. The programme’s budget is around € 95.5 billion, of which € 5.4 billion is from NextGenerationEU to stimulate recovery and strengthen the EU’s resilience in the future, and € 4.5 billion is additional aid.
This initiative seeks to boost Europe’s developer community and accelerate the adoption of trustworthy Generative AI in three strategic sectors crucial for competitiveness: aerospace, pharmaceuticals, and telecommunications. In pharmaceuticals, GenAI can revolutionise drug discovery by rapidly generating target-specific molecules, reducing development time from years to seconds, and helping to prevent health crises such as COVID-19. In aerospace, it can optimise aircraft design, streamline manufacturing, predict maintenance needs through sensor data, improve route planning, and enhance pilot training with realistic simulations. In telecommunications, it enables the creation of intelligent and automated networks with applications in network management, optimisation, healing, slicing, predictive maintenance, and mapping. Proposals must focus exclusively on one sector, design and implement a multi-stage competition around industry-driven challenges, and provide participating companies with technical guidance, business mentoring, and access to data. Strategic industry players should be core partners, ensuring the work is relevant and impactful. While the outcomes will be pre-competitive, each proposal must include a draft exploitation plan, with the consortium responsible for guiding the competitions and supporting participants in developing powerful, industry-ready solutions.
Proposals should be driven by impactful use-cases where generative AI can make the difference: a number of industries from the targeted sector are expected to join forces to define challenging problems to solve with GenAI solutions, which then drive the rest of the project. Based on such challenges, the consortium organises a multi-staged competition with an increasing level of complexity. In the first two stages, third parties, either single companies (typically start-ups or SMEs) or small team of organisations built around such start-ups/SMEs, compete to address the challenges with GenAI solutions. After these stages, the solutions retained for the last stage will be invited to join the consortium, as full beneficiaries.
For each proposal:
Such multi-staged scheme is expected to be implemented in parallel by the successful proposals, each addressing a different sector.
Each proposal, involving several major industry players, should define a clear methodology to implement the various steps of the approach, define the specifications of the stages of the competitions, timelines, targets, KPIs, a solid evaluation methodology including evaluation criteria. The main information should be in the proposal, even if refinements could be further developed during the project. The proposers will also be in charge of implementing the evaluation methodology, and providing the necessary infrastructure/technical support for the participants to the challenges. The consortium members are also responsible for ensuring high visibility of the competitions, including possible sponsorships.
The actions selected from this call, each addressing one of the three targeted sectors, are expected to collaborate among themselves, in order to make economies of scale in sharing best practices, defining processes for organising the challenges, ensuring efficient monitoring, organising dissemination and communication activities, etc. Such collaboration among the linked actions is expected to be formalised by a collaboration agreement, after the Grant Agreement signature.
For each proposal, an amount of EUR 5 millions is foreseen to be distributed among the winners of stage 1, in form of FSTP grants, in order to prepare for stage 2. In addition, a budget of EUR 8 millions is reserved in the initial grant, to carry out the stage 3 of the challenge. The proposal is expected to make the case for such investment in defining the objectives with sufficient level of information, even if the details are to be further elaborated in the course of the project. Such amount will be distributed equally among the 4 winning teams of the stage 2, who will be invited to join the consortium as beneficiaries to develop further the solutions and compete for the stage 3 of the challenge.
Visibility would be important; therefore dissemination and communication campaigns are key. The proposers are also encouraged to seek sponsorship, which would be key for the visibility and prestige of their challenge, and to attract the best developers from the EU and associated countries to compete, particularly SMEs and startups, alone or within a team competing for the challenges.
All proposals are expected to incorporate mechanisms for assessing and demonstrating progress, including qualitative and quantitative KPIs, benchmarking, and progress monitoring. This should include the methodology to accompany the challenge participants to the various stages during the project, and the assessment methodology during the various selection stages. As part of the KPIs, efficiency gains from Generative AI should be considered, to maximize broader impact.
When possible, proposals should build on and reuse public results from relevant previous funded actions. Communicable results should be shared with the European R&D community through the AI-on-demand platform, and if necessary, other relevant digital resource platforms to bolster the European AI, Data, and Robotics ecosystem by disseminating results and best practices.
This topic implements the co-programmed European Partnership on AI, data and robotics (ADRA), and all proposals are expected to allocate tasks for cohesion activities with ADRA and the CSA HORIZON-CL4-2025-03-HUMAN-18: GenAI4EU central Hub.
Proposals should also build on or seek collaboration with relevant projects and develop synergies with other relevant International, European, national or regional initiatives.
100%
Expected EU contribution per project: €15.00 million.
Beneficiaries must provide financial support to third parties. The support to third parties can only be provided in the form of grants. In derogation to article 208 EU Financial Regulation, the maximum amount to be granted to each third party can exceed €60.000 and reach up to €250.000 per competing solution. This derogation is justified by the substantial resources required to successfully carry out the challenges planned in the project in the stage 2, that should be substantiated in the proposals. This amount is granted at the end of the first stage of the challenge to the 20 winning solutions, as a grant to prepare for the stage 2 of the challenge.
Each competing solution to be developed in stage 2 is proposed either by a single start-up/SME or a small team of organisations built around such start-up/SME, therefore the €250.000 is distributed accordingly.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects.
Participation is limited to legal entities established in Member States, Iceland and Norway and the following additional associated countries: Canada, Israel, the Republic of Korea, New Zealand, Switzerland, and the United Kingdom.
Entities established in an eligible country listed above, but which are directly or indirectly controlled by a non-eligible country or by a non-eligible country entity, may not participate in the action unless it can be demonstrated, by means of guarantees positively assessed by their eligible country of establishment, that their participation to the action would not negatively impact the Union’s strategic assets, interests, autonomy, or security. Entities assessed as high-risk suppliers of mobile network communication equipment within the meaning of ‘restrictions for the protection of European communication networks’ (or entities fully or partially owned or controlled by a high-risk supplier) cannot submit guarantees.
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Persons to Contact:
Dr Angelos Ntantos
Scientific Officer
Email: antantos@research.org.cy
Mr. George Christou
Scientific Officer
Email: gchristou@research.org.cy